Key molecular pathways in ALS
From MyWiki
For very comprehensive pathway diagrams for LMN ALS see, https://files.acrobat.com/a/preview/646bf152-9ef2-4f51-8d4a-cb8e9fc0a4ac
| Pathway | Type | Activated by | Inhibited by | Activates | Inhibits |
|---|---|---|---|---|---|
| NF-kappaB | Inflammatory | ||||
| TNF-alpha | |||||
| caspase-3 | |||||
| AMPK-α1 | |||||
| IL-10 | |||||
| SARM1 | |||||
| PKC | |||||
| VEGF |
