Leucine

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Information on nutritional supplements people with ALS have been taking

Wikipedia on leucine

  • α-amino acid used in the biosynthesis of proteins.
  • contains an α-amino group (which is in the protonated −NH+3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and an isobutyl side chain, classifying it as a nonpolar (at physiological pH) amino acid.
  • essential in humans—the body cannot synthesize it and thus must obtain from the diet.
  • a major component of the subunits in ferritin, astacin, and other "buffer" proteins.

Examine.com on leucine

Effect of leucine on ALS

Discussion threads on the ALSTDI forum

Regulated pathways

Where to get it

References