Leucine

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Wikipedia on leucine

  • α-amino acid used in the biosynthesis of proteins.
  • contains an α-amino group (which is in the protonated −NH+3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and an isobutyl side chain, classifying it as a nonpolar (at physiological pH) amino acid.
  • essential in humans—the body cannot synthesize it and thus must obtain from the diet.
  • a major component of the subunits in ferritin, astacin, and other "buffer" proteins.

Effect of leucine on ALS

Discussion threads on the ALSTDI forum

Regulated pathways

Where to get it

References