Key molecular pathways in ALS

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{̺{tip|For very comprehensive pathway diagrams for LMN ALS see, https://files.acrobat.com/a/preview/646bf152-9ef2-4f51-8d4a-cb8e9fc0a4ac}}

{̺| class="wikitable" ! Pathway || Type || Activated by || Inhibited by || Activates || Inhibits |- | NF-kappaB || Inflammatory |- | TNF-alpha |- | caspase-3 |- | AMPK-α1 |- | IL-10 |- | SARM1 |- | PKC |- | VEGF

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