Editing Key concepts in ALS

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[http://alsanesthetics.org/guest_repo/rmattila/big_picture_mindmap.html The Big Picture Mindmap]
 
 
[[Aberrant astrocytes]]
 
 
[[Ammonium hypothesis]]
 
 
 
[[Apoptosis]]
 
[[Apoptosis]]
 
[[Autophagy]]
 
 
[[Biomarkers]]
 
  
 
[[Calcium homeostasis]]
 
[[Calcium homeostasis]]
 
[[Clinical trials]]
 
 
[[ER stress]]
 
 
[[Excitotoxicity]]
 
 
[[Exosomes]]
 
  
 
[[Genetic abnormalities]]
 
[[Genetic abnormalities]]
 
[[Glutamate]]
 
 
[[HDAC activation]]
 
 
[[HSF1]]
 
 
[[HspB8]]
 
 
[[Hsp104]]
 
 
[[Hypoxia]]
 
 
[[Iron metabolism anomalies]]
 
  
 
[[Lab abnormalities]]
 
[[Lab abnormalities]]
 
[[Leaky gut]]
 
 
[[Lipopolysaccharides]]
 
  
 
[[Loss of BBB integrity]]
 
[[Loss of BBB integrity]]
  
[[Macropinocytosis]]
+
[[Mitochodrial dysfunction]]
 
 
[[Mitochondrial dysfunction]]
 
 
   
 
   
[[MMP-9]]
 
 
[[NAD depletion]]
 
 
 
[[Nerves that resist destruction]]
 
[[Nerves that resist destruction]]
  
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[[NMJ faults]]
 
[[NMJ faults]]
 
[[Nrf2]]
 
 
[[Oligodendrocytes]]
 
  
 
[[Oxidative stress]]
 
[[Oxidative stress]]
  
 
[[Prion-like properties]]
 
[[Prion-like properties]]
 
[[Proteasome]]
 
 
[[RNA transcription]]
 
 
[[Skin changes]]
 
  
 
[[Stress granules]]
 
[[Stress granules]]

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