Editing Inosine
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Inosine antagonizes glutamate-induced electrophysiological excitation in rat cerebral cortical neurons.{{#pmid:15692110|Shen2005}} | Inosine antagonizes glutamate-induced electrophysiological excitation in rat cerebral cortical neurons.{{#pmid:15692110|Shen2005}} | ||
− | Inosine protects rat oligodendrocytes from hypoxic injury as an antioxidant and ATP provider, and the protective effects of inosine on oligodendrocytes vary with cell differentiation, possibly due to the adenosine receptors expression profile. | + | Inosine protects rat oligodendrocytes from hypoxic injury as an antioxidant and ATP provider, and the protective effects of inosine on oligodendrocytes vary with cell differentiation, possibly due to the adenosine receptors expression profile. [5] |
In mouse spinal culture under hypoxic conditions, inosine preserved both total cell and neuronal viability in a concentration-dependent manner.{{#pmid:10064830|Litsky1999}} | In mouse spinal culture under hypoxic conditions, inosine preserved both total cell and neuronal viability in a concentration-dependent manner.{{#pmid:10064830|Litsky1999}} |