Editing Information on nutritional supplements people with ALS have been taking
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| − | + | This is a list of supplements people with ALS have reported taking. Along with each supplement, its supposed pathways of functioning are given, along with typical dosages and potential side effects. The aim is to create a specific data page on each supplement, along with links to scientific research articles etc. | |
| − | + | 5-HTP Serotonin upregulator Risk for serotonin syndrome if many serotonin boosters are taken at the same time. Capsule 100 mg, twice a day | |
| − | + | Acetyl L-carnitine (ALCAR) Mitochondrial support Capsule | |
| − | + | Alpha ketoglutarate (AKG) Krebs cycle support Capsule 3 - 20 g a day | |
| − | + | Berberine Anti-microbial Capsule | |
| − | + | Berberine AMPK activator Excessive AMPK activation may induce TDP-43 mislocalisation. Possibly detrimental in SOD1 ALS. Capsule | |
| − | + | Curcumin Anti-inflammatory (general) Consult a doctor first if you have problems with gallbladder. Capsule 400 mg, once a day (in the morning) | |
| − | + | Dexthromethorphan Anti-bulbar/pseudobulbar symptoms Liquid | |
| − | + | Dichloroacetate (DCA) Glycolysis inhibitor Severe, including peripheral neuropathy if taken too much or for too long. Powder 2 g a day | |
| − | + | European milk thistle extract Mitochondrial support Softgel 500 mg, once a day | |
| + | Gastrodia elata Endothelin-1 downregulator Capsule | ||
| + | Ibuprofen Anti-inflammatory (general) Stomach issues that do not vanish over time. Pill 200 mg, twice a day | ||
| + | Inosine Axon growth stimulation Capsule 500 mg, once a day | ||
| + | Inosine Elevates uric acid Capsule 500 mg, once a day | ||
| + | Leucine GDH activator Powder 1 g a day | ||
| + | Magnolia bark extract Anti-anxiety Capsule 30 mg, 2-4 times a day | ||
| + | Magnolia bark extract Anti-bulbar/pseudobulbar symptoms Capsule 30 mg, 2-4 times a day | ||
| + | N-Acetyl-cysteine (NAC) Glutathione synthesis Capsule 600 mg, twice a day | ||
| + | N-Acetyl-cysteine (NAC) Prevents TDP-43 misconfiguration Capsule 600 mg, twice a day | ||
| + | Niacin (vit. B3) | ||
| + | Niacinamide (nicotinamide) | ||
| + | Nicotinamide riboside | ||
| + | Peony root extract | ||
| + | R Lipoic acid Mitochondrial support Capsule 300 mg, once a day | ||
| + | Resveratrol AMPK activator Excessive AMPK activation may induce TDP-43 mislocalisation. Possibly detrimental in SOD1 ALS. Capsule | ||
| + | Resveratrol Inhibits PGE2 Excessive AMPK activation may induce TDP-43 mislocalisation. Possibly detrimental in SOD1 ALS. Capsule | ||
| + | Selenium Glutathione synthesis Pill 0.1 mg, once a day | ||
| + | Sodium benzoate Ammonia scavenger Needs arginine supplementation to be fully effective Powder 2-4 g a day (?) | ||
| + | Taurine | ||
| + | Trimethylglycide (TMG) Homocysteine suppression Capsule 750 mg, twice a day | ||
| + | Ubiquinol (COQ-10) Mitochondrial support Capsule 100 mg, once a day | ||
| + | Vitamin D Anti-inflammatory (general) | ||
| + | Vitamin K Calcium management | ||
| + | Zinc gluconate Copper inhibitor Copper deficiency if taken in excess. GDH downregulation? Capsule 25 mg, three times a day | ||
