Editing Autophagy
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*[https://en.wikipedia.org/wiki/Autophagy Wikipedia page] | *[https://en.wikipedia.org/wiki/Autophagy Wikipedia page] | ||
− | + | * allows the orderly degradation and recycling of cellular components. | |
* In macroautophagy, targeted cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. | * In macroautophagy, targeted cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. | ||
* The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. | * The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. | ||
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* In disease, autophagy has been seen as an adaptive response to stress, which promotes survival, whereas in other cases it appears to promote cell death and morbidity. | * In disease, autophagy has been seen as an adaptive response to stress, which promotes survival, whereas in other cases it appears to promote cell death and morbidity. | ||
* In the extreme case of starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels. | * In the extreme case of starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels. | ||
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[[Category:Key concepts]] | [[Category:Key concepts]] |